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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01159dcac52a0af00abcf33ceeadc01b3757ba6fc51eb34b7666a4573e98aea9' 
  AND token = 'V0XlYRW5mEwtjvqIFjpXTGf8ZUuUkIkOimMyjg0+xmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}