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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b9746e9c6e9504c157ece95c016d767e7b1eef73b5d6bfad8ca77269c7090e2' 
  AND token = 'JAq43d5PQMTqFYpTWbMHDBImqvZGCbBdGwo3ya4WZRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}