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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd62040fe759f41c065a7521e7b61567a9f969693de4f76f31264b29b67b6c56a' 
  AND token = 'S6i7zoopATdb1Bhg+RLpxjKGSLjMvA18X2EXFY0WkHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}