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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7e698c12386144d82cb0e1359c9c3c4ac6f72ed0fa8b914fdc6c458d2d4473' 
  AND token = 'QG2mJvtii/1jMTy5gxQ/R8sFIdc6G+qbMBLdK9c57UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}