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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8e2f135e86a933a77d234f948a8172cf93626a3f234405f8a4dd37f0d86407' 
  AND token = 'dtjboeOP8l9QBxck2lO4l9YK+eBMQP/NO+eZ/kj+RPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}