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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0103156e7abd8ee63312dc14b222dc30785aa4eb46d3dbd487a413f95dff54' 
  AND token = 'NWSJ66XWOCKZrjmYL9H+b6Smn0WtU+v8wLfIQ6IUxEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}