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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a478b247d59860bec7b748824e45f87e1fe981f1ac3fa2ca274453ff48351d' 
  AND token = 'k4wiN2CHDF+K7cYddYjx1yZVioIC29jbYVcQBCtTnsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}