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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb67205e36baff454263c8f7a218c5c5eca7bc94bd45fdfc3e368c1f1ab2423' 
  AND token = 'HLNxx9xbx7SdT+sfPGgrW5/NFTWXKMslVPfAg0I4Qvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}