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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4d355c7755885d3d14074d4f38c5e74644c0e42798714c277715f7d9f8ab6f' 
  AND token = 'A5bheLcG3s2qkf8Uqsdf6mhM6+vPtjBEG4l4/VWc78E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}