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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb421a49e09b3da4874c962415675e5a86d64881a6c4bed71f0996b324bfc38' 
  AND token = '3svpWfNi8tbOCCLr8eyempTaA5gAdFRoAO7fXoir+9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}