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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b2c749afd6bff7b935ed0f7b254fcc162819d39760addde4f07aa83bddf47a' 
  AND token = '5HYOX/lSP0U2LDwWYYgHalZb7v3ET7KftXW/uOxsV9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}