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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469b423fe00bedd362d19047c5e19cbbb241e1fc4f01163d3dbb40cee4946745' 
  AND token = 'gh00K5ifwTWRbKfK09LMnYvvcBl6PLkylvTnf+P3w/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}