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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afdff95fac18845de147a4aec036373c924d3b5e231e4f3b6d25ce2fcc12b38d' 
  AND token = 'STxuCQkZT61WO7LS8NM4DaCJ8kDiCPB08cHe8YosnXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}