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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f603820c3060da7f2e424ec4c036b8f93e30634c8cced6dac2cbdf9b9fe790b' 
  AND token = 'AkDU5xBWSxJEY/vZKqhXTC/dEE3tvyhA8r2kZXSjCaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}