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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2cde8f097a402ec9bb07b0d930b38939b3857582a04e2afc5a888279b5f329' 
  AND token = 'SWk+QYiu9TJQc+oIWS9R6eYAe+vggFbX8JE2qJ40eZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}