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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4eb26a6dd120eaa90117d6c33a6a0181ae48402964b4f8c18721cdec384629' 
  AND token = '/oEpcq65w7diCE2qFrCAFtyzPpw9cJZhBgBWbqZxSrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}