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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152810d5f6b01b36d1523a50c1a644393b302dcd0334784f677d3e21f96bde5a' 
  AND token = 'MY8FIcFph7On59bTosWaRbwpBR7ukgvFModYTBd8Hr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}