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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d40f5ecb9767fe828f768a43d33383797a1981efae423e78bf7a8ad359a6066' 
  AND token = 'oH45YpM16Yks6w1O5Z5s0bzoW25VKooeD01+s6XIlJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}