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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821afd98fbf29852654f8e5e3733dc36d579b4743d819f90ba621d21d7880705' 
  AND token = 'TmWMHB7Qqux7OkkAKne6XDbsud7FMp9JtVRL4TS4jQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}