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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfad4c8591651fb77ca6ef6632ce9c5381d6657abaad16f465702cc318f57b4' 
  AND token = 'yFyA3wrgczrPRC7aI/qeo1OwdHHarJQts3yWiJ8v9Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}