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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6621788a4421b78b0ea28f5064d15343426ee7b975c8a3830eb95f192d5f372d' 
  AND token = 'beECYqnKmjLP0VV68mWU0lHiHCSub02vV7bk7cpnIOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}