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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a060cdb37ecb199396a747816f507b271710a1ea05eb5a5a8e57dd69ab19339' 
  AND token = 'h4Mg24Tpw1Jqca/BoQJvj6C6mJvmmMh7ZiDH2Ura8DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}