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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f6b186447b754413cd9e0de24e3667922651ff1c1dc341ebd3584f43da2d8a' 
  AND token = 'F729zs8HmgVPy88dl9GAtXqG/QQX62NbugpPriN0hPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}