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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b42b749b21195c7665999fb2c6e5bdb7bef79c543e00c24ccf86e177958d86' 
  AND token = 'V3Fb88ldA/g28CbNH2zuHi5Nfb01X9R4oVROZ2zFovU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}