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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565eef47ab6ec06468ed44902da90f22fafe420ccf27bc3f6880207fae1ae9fb' 
  AND token = 'KNxgN+W0JBuZ/V8ttX5QpRpkKOV/8EYPglpd26ZuOZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}