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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3958de0709acb95c494f250f3e5b05797162d4a5df1f820bef6839fb62403a' 
  AND token = 'j7Fl8K60WsQPDsrnLaUDtGUr/0yu0y/9qGC8WRyJqSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}