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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bc9b45d8d14aaf82243d8d5b7b9e32bba84e2c79905ea50dc68bc466b41508' 
  AND token = '5PkrOmuUKnRtX0zY3kaxlesbAI2hstqlMD9n5jrXduw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}