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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7beaf841dfc5d2b87f4523e01cbb3c81935a1041249433c0f6e90b139753692' 
  AND token = 'VXHUWS0cW9dXURTNXl5zY0b/hj30Yjdj+WMKpOrpyHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}