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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27b0213e4894cdf3fb953e80a8be765221b32235c915760d9ecf2303069d6bb' 
  AND token = 'WTq4e7JN9nOIWDQUfMmku1bt8PiKNFs9frrMeTzeXgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}