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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f07baf28b01e350e2c2489b2408fa0888219f8206cc3b4d0d7f338537e06ad4' 
  AND token = 'dBWtbdbK+KsEvkAIwzVKt4x4HA0xFg0F1797hv4wKKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}