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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1788b49b787cb8a7accbe5a2a2250a7914b275bab5b76a2b6ce8fd0e24c97842' 
  AND token = '3OZKeP+GcfxUbxV3J6hvWNRhZ3a4Lgq0evu2bK5ifkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}