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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6113012e50c2e3021da10be0e67372629c6554c82d77c6cb3e4c7020a4aa6df9' 
  AND token = 'ccpy+Stmp3UKTA2ErD4HVfz+E7UYs4DXvQSYfYV/X4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}