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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce3e60bdc6a9c95cc9b73dabd3e1a82ce9512c8b39c330df219b573f9e22094' 
  AND token = 'xNjvfhUFVGVr+ePUamNY6A3NGA6MxRq6Wx0BqrfbakQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}