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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0e8f1c419ce3ab75b87be8d348c6aa40e81dedd97d2df65000176e75756211' 
  AND token = '8W+y0QDpxOrxdRLYX/+XnIRIGQRknuSpxCcyPXhE9DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}