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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2327d3064999fc0fb664dbcbcefa60fa7b08f79f19683a34518c977f70a2186d' 
  AND token = 'Ma2m/fM+I8ZIX2fqv5wfXYa3c5VFBt/okr3n9y0zSgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}