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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ccce2b09e6846463e12fdfcc04dff20bfe8230667ba6752e2b8e322223026b1' 
  AND token = 'fD0ht+DLfZSPxIw3oq8FjyZQHb0ePZiC2ZOXhXWocCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}