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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59c722dd45ed7899f1d71b2b5e72a7899b4e56dc13d30fde3b5d51714fc77cc' 
  AND token = 'FcdjBEQHi3/Rh/VcDbLZbQBW+XWdNnDk/zHzwVFIft4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}