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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8826ff48fc24d6c52de42e61900ef7e5e110e06bd1e82c7b82e799e3af114329' 
  AND token = 'XDwP4EkXadeBJ3Z/jTLq1Ojl49PeXioCPzn3LxTb3Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}