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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784dcb7d1f41d578eb3fcdbe7ca01d340b22f9c14f6c7d3004e6061e5dd32b05' 
  AND token = 'soSEr73DpehCaSNm3K7pNa+kJbQiT6bbpF+vlwIb8M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}