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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541b74ce461e7871fabab7544e4550b1339533e26add93fc55fdc6360c1d037a' 
  AND token = 'rC3tMMF1JOi1T/3Zn1r/uBngqQx4wi82GCH98lT8Fa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}