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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '974bbe10c1b433d9f53bef02aa71f561c04b50a8be884c7d215a0c4d1dcf715d' 
  AND token = 'L1LcN/+LQO12KoByK9Gwe+q//lDcKuUI/FxBVKaUvQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}