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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31705a3d0d0b2d27b20ffe7d44f234375cb40ea0e48f37c2585406bd6d35a5f' 
  AND token = 'CmL/n3cejB5ZuaQOWbbpS/7jrWHNoV6w0FRONI5d+YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}