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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b13b2da2be97fef48887a10a22ab628d1769d7b27a4f42dc55314a5cd9666f' 
  AND token = 'ZfiPZeWGirBapJ7FfZBGbNvVaUpXxc4IDZpVEUMiJd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}