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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53e74971f10dea894f95e8cb844f622a280f8c69fea86f305115d87ca3f0af9' 
  AND token = 'PjqrbOg6wyaP7ySCYaJ1TxGlyEzxSd4KYh3Xm++4ywc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}