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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ffc0610a61d98cfefe6240a0beb601a26863c0fac3be67aa35b3c4250fa57d' 
  AND token = '2jrazuPkLs1/AdjeLj0In82G0wZsyiaJ79VZAV1CVT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}