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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4fb2cb68f163116fd0f47d1129b44dfc46f0434e4d4b71e380d78c1de8b4abe' 
  AND token = 'yBgMOGBd8v450nuBa/SnzEyTBqrcPTBBIRRWgxCjaKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}