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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2441dcdb9127eb99854788c60700235cc8bf41eb97cd55f345a09656a8f86d9' 
  AND token = '27dyxNv7oNB20pbeXXzenYmw9v8lIB0YL8vP5nExYCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}