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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a03d35b1f731082da7f31e873fb96eb3864f5c0b73daf0bb0f171340ed48d6' 
  AND token = 'Tx9ud/EeHJscgnmLbcRIu8Q4tDyA//iCi7msEgntIfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}