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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46017320ee28382d01e58f7fd16ecf913fe90c36e5c297328f7ecc5c0a68b27d' 
  AND token = 'b3Si1h47BUk0Qjm8Q6n+2cakeoMg79vW+ugH2uCzO8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}