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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e296a89169358ac95fdb1d9e7ffe80f43f5a75882d1d1f2c1fe2040c3d5fe843' 
  AND token = '+iI2wEpB9k/VG7m5icM2hbzfg3qaBPMGdkkc/OTzAWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}